mtl008 Chapter 848: 3 Pharmaceutical Technical Data
Chapter 848: 3 Pharmaceutical Technical Data
Having Penicillium strains is equivalent to having seeds. Even if there is no research data on deep liquid fermentation technology, more Penicillium strains can be cultivated in the laboratory to extract more penicillin.
Zhang Yunhe shifted his attention to the metal safe next to him. This thing was embedded in the reinforced concrete wall. He didn't have the strength to pull the entire safe out of the wall. He could only find a way to open the safe and see what information was stored inside.
Zhang Yunhe discovered that the lock of this safe was a combination of a rotary mechanical lock and an electronic lock. Yes, a push-button electronic lock!
He hadn't expected that electronic locks had already appeared in this era. This was the first push-button electronic lock he had seen since he came to this era.
Through observation, he found that this was one of the earliest push-button electronic locks. Due to technical limitations, this type of electronic lock could not be widely popularized.
As far as he knows, the subsequent popularity of electronic locks was due to the invention of power supply technology and integrated circuits.
This earliest electronic combination lock might not be openable by other agents who have not had access to it, but it is not a problem for him at all. Even if it is a smart electronic lock from later generations, he can crack it with the Iron Blood computer.
He first used a stethoscope to open the mechanical lock of the turntable knob, which took two minutes.
Then he scanned the buttons on the electronic combination lock, and only the three buttons 479 had fingerprints on them.
“这种最初的电子锁应该不具备按错键就锁死的功能，只有这三个按键有指纹，那就这个密码就只有几种可能，分别是479、497、749、794、974、947”
Zhang Yunhe muttered to himself and immediately began to try one by one. When he pressed the three keys 794, there was a "click" sound from the safe.
Zhang Yunhe was calm. He reached out and turned the door handle, and the safe slowly opened.
There were three thick file bags inside. Zhang Yunhe took out the top one and saw a sticker saying "Laboratory Research and Preparation Technology of Tolbutamide" on it.
"Tolbutamide? What kind of medicine is this?" Zhang Yunhe opened the file bag puzzled and took out the information inside to read it.
The material begins by telling the story of a French doctor who discovered that sulfa drugs have the effect of lowering blood sugar while treating patients with typhoid fever. After this discovery was announced, the medical community began to develop drugs for the treatment of diabetes based on sulfa drugs. The drug tolbutamide was developed based on sulfa drugs for the treatment of diabetes.
However, this drug has just been developed and animal experiments only began a month ago. There is not much research data at present, but it is certain that it has a good blood sugar-lowering effect and is beyond the scope of antibiotics such as sulfonamides.
After all, diabetics cannot lower their blood sugar by taking oral antibiotics such as sulfonamides because the side effects and harm are too great. However, according to existing experimental data, no obvious side effects of tolbutamide have been found in animal experiments.
Zhang Yunhe didn't know much about the development of Western medicine, but he felt that this might be a new drug for treating diabetes, so he put it into his backpack.
He picked up the second file bag, which contained the industrial production technology data of sulfonamide.
As far as he knew, although the industrial production technology of sulfonamides was not top secret, it was not something that ordinary pharmaceutical factories could easily master.
The Germans were the first to start the research and manufacture of sulfonamides. They developed sulfamethoxazole in 1936, but at first it was only enough for laboratory use. Later, the production was increased and some of it flowed into the market. Zhang Yunhe first sold sulfa drugs that were shipped from Germany.
However, due to the war, the British first built the first large-scale mass production factory of sulfa drugs, with a monthly output of 3 tons.
The industrial production technology of sulfonamide has reduced the cost by 80% through technical improvements in the fermentation process!
Seeing this description at the beginning of the document, Zhang Yunhe took a breath and said, "Reducing costs by 80%?"
"Oh shit!" Zhang Yunhe was overjoyed. This is a mature industrial mass production technology!
Received, received!
The antibacterial effect of sulfonamide is so great that it has reduced the surgical infection rate from 40% to 8%; it has reduced the mortality rate of pneumonia by 75% and has given rise to the modern pharmaceutical industrial system.
Zhang Yunhe picked up the last document, which had the words "Penicillin Liquid Submerged Fermentation Technology" clearly pasted on it.
The purpose of this trip was achieved, and Zhang Yunhe breathed a sigh of relief.
He had just put the information into his space backpack when he suddenly thought of something. After thinking about it, he took out the three technical documents one by one, and then took out a miniature camera to take pictures of the three documents one by one.
It took him more than half an hour to take pictures of the contents of the three documents and then put them back to their original places.
Then take out the metal password box containing the Penicillium strain, open it, take out the three bottles of strain inside, tear off the labels, and take out three identical brown glass bottles from the backpack space, stick the labels on them, and put them back into the metal password box, and return the password box to its original place.
If you don't take the fungus strains out of the glass bottle, it would be impossible to discover that the fungus strains have been swapped, and it would be impossible to discover that the technical research data has been stolen.
After coming out of the secret room, Zhang Yunhe saw the two attendants still sleeping on the table. He quietly walked out of the archive room, closed the two doors one by one, and left the experimental building before the patrol team came to inspect.
After hiding in a secluded place, he quickly drove away in a landing craft.
It was night when we returned to Hong Kong Island. Due to the blockade by the Japanese, the port had almost come to a standstill. There were no ships entering or leaving the port, and naturally there were no people in the port.
After Zhang Yunhe put away the landing craft, he immediately took out all the food and daily necessities he brought back from the backpack space and piled them in the warehouse and open field.
After finishing, he called the head of the Third Regiment.
The call was quickly connected: "I am Gu Dalei"
Zhang Yunhe said, "Gu Dalei, bring your men to the dock yourself. A batch of food and daily necessities has arrived!"
"What? Food is being delivered? Okay, I'll bring people here right away!" Gu Dalei shouted in surprise. It was obvious that he also knew that the food reserves on the island were only enough for everyone to eat for one month, and not a single bit could be wasted.
Now we have food, although we don’t know how much, but at least there is hope.
When he arrived at the dock with a company of men, he was shocked to see the mountains of food.
"How much food is this? How long will it take to eat?"
Zhang Yunhe said, "With the current population of 180 million on the island, if each person gets half a pound of food per day, that's enough food for three years!"